虎眼万年青的化学成分

目的：研究栽培于长白山区的虎眼万年青Ornithogalum caudatum Ait全草的化学成分。 方法：用各种色谱技术进行分离和纯化，用ESIMS,IR,¹HNMR,¹³CNMR,DEPT,¹H-¹H COSY, ¹H-¹³C COSY, HMBC和NOESY等波谱数据分析鉴定结构。结果：从虎眼万年青全草中分离得到3个化合物，其中化合物I为新化合物,其结构鉴定为（25S, 23S, 24S）-螺甾-Δ⁵⁽⁶⁾-烯-1β, 3β,23,24-四醇-1-O-α-L-吡喃鼠李糖基-（1→2） ［β-D-吡喃木糖基-(1→3)］-α-L-吡喃阿拉伯糖苷(I)，另外2个已知化合物为海柯皂苷元-3-O-{β- D-吡喃葡糖基（1→2）-［β-D-吡喃木糖基（1→3）］-β-D-吡喃葡糖基（1→4）-β-D-吡喃半乳糖苷}(II)和β-谷甾醇(III)。结论：化合物I为新化合物，命名为虎眼万年青苷A，化合物II和III是首次从该植物中分得的已知化合物。

STUDIES ON THE CHEMICAL CONSTITUENTS FROM ORNITHOGAUM CAUDATUM AIT

AIM：To investigate the chemical constituents of the whole plant of Ornithogalum caudatum Ait. METHODS: Various chromatographic techniques were used to separate the chemical constituents. ESIMS, IR, ¹HNMR, ¹³CNMR, DEPT, 1H-1H COSY, ¹H-¹³C COSY, HMBC and NOESY were used to determine the structure of the isolated constituents. RESULTS: Three compounds were isolated from the whole plant of Ornithogalum caudatum Ait. They were identified as (25S,23S,24S) spirosta-Δ⁵-ene-1β,3β,23,24-tetral-1-O-α-L-rhamnopyranosyl(1→2)-［β-D-xylopyranosyl(1→3)］-α-L-arabinopyranoside(I); Hecogenin 3-O-［β-D-glucopyranosyl-(1→2)-［β-D-xylopyranosyl-(1→3)］-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside］(II) and β-sitosterol (III). CONCLUSION: Compound 1 is a new steroidal saponin and was given the name caudaside A. Compounds II and III were obtained from this plant for the first time.