北京市顺义区384例麻疹疑似病例血清学检测结果

目的分析北京市顺义区麻疹的流行情况,评价麻疹疑似病例的血清学诊断。方法对2005年1月—2008年12月麻疹疑似病例的流行病学调查和血清学检测结果进行分析。结果384例麻疹疑似病例麻疹IgM抗体阳性率为66.93%。不同年龄组间IgM抗体阳性率差异有统计学意义,8月龄组和≥20岁的成年人组IgM抗体阳性率较高,而8月龄～4岁及5～20岁组阳性率较低。不同免疫组间IgM抗体阳性率差异也有统计学意义,有免疫史组的阳性率低于无免疫史及免疫史不详组。不同采样时间IgM抗体阳性率不同,出疹当天采集的血清阳性率最低。结论继续作好麻疹疫苗的常规免疫和强化免疫工作,控制成年人麻疹病例的发生,提高麻疹实验室监测的敏感性和准确性,促进麻疹的控制与消除。

Results of Serological Testing on 384 Cases of Suspected Measles in Shunyi District of Beijing City

Objective ] To analyze the incidence of measles in Shunyi District of Beijing City, and evaluate the serological diagnosis of suspected measles cases. Methods ] Results of epidemiological survey and serological tests on suspected cases of measles from Jan. 2005 to Dec. 2008 were analyzed. Results] The positive rate of IgM antibody among 384 measles cases was 66.93% ; signifi- cant difference existed among age groups; the positive rates were higher in 〈8 months age group andS20 years adult group, and lower in 8 month - 4years age group and 5 ~ 20 years age group, that between groups with different imunity history was significantly different, and lower in the immunized group than the non-immunized group. Positive rates were different among groups with different serum-collecting time, and lowest in the group whose serum was collected on the eruption day. Conclusion ] Conventional immunit）＇ of measles vaccine and strengthening of immunity should be further performed to control the incidence of measles among adults. The sensitivity and specificity of surveillance of measles,in laboratory should be improved to contribute to the control and elimination of measles.