| 阿德夫韦酯联合扶正祛淤对慢性乙型肝炎患者肝纤维化指标的影响 |
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| 引用本文： | 张云涛,孟明星,李焱,幺作义,李纯平.阿德夫韦酯联合扶正祛淤对慢性乙型肝炎患者肝纤维化指标的影响[J].现代预防医学,2011,38(11):2167-2169. |
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| 作者姓名： | 张云涛 孟明星 李焱 幺作义 李纯平 |
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| 作者单位： | 河北省唐山市传染病医院,唐山,063000 |
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| 摘 要： | 目的]观察阿德夫韦酯(ADV)联合扶正祛淤治疗慢性乙肝(CHB)的临床疗效及对肝纤维化指标的影响。方法]100例CHB患者随机分为治疗组和对照组。对照组给予ADV治疗,治疗组给予ADV联合扶正化瘀治疗,疗程为1年。疗程结束后评价临床疗效。治疗前和疗程结束后测定血清肝纤维化(PCⅢ、Ⅳ-C、LN、HA)水平。结果]治疗组临床疗效总有效率为94.0%,显著高于对照组(76.0%),相比较差异有统计学意义(P﹤0.05)。治疗后,两组患者血清肝纤维化4项(PC-Ⅲ、IV-C、LN、HA)水平显著下降(P﹤0.05),与治疗前比较差异有统计学意义(P﹤0.05),且治疗组与对照组比较差异有统计学意义(P﹤0.05)。两组均无不良反应。结论]ADV联合扶正化瘀治疗CHB能够阻止或改善肝纤维化,临床疗效明显,值得临床推广应用。
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| 关 键 词： | 慢性乙型肝炎 肝纤维化 阿德夫韦酯 扶正化淤 |
INFLUENCE ON LIVER FIBROSIS OF CHRONIC HEPATITIS B USING ADEFOVIR DIPIVOXIL COMBINED WITH FUZHENG HUAYU CAPSULE |
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| ZHANG Yun-tao,MENG Ming-xing,LI Yan,et al..INFLUENCE ON LIVER FIBROSIS OF CHRONIC HEPATITIS B USING ADEFOVIR DIPIVOXIL COMBINED WITH FUZHENG HUAYU CAPSULE[J].Modern Preventive Medicine,2011,38(11):2167-2169. |
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| Authors: | ZHANG Yun-tao MENG Ming-xing LI Yan |
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| Institution: | ZHANG Yun-tao,MENG Ming-xing,LI Yan,et al.(Infectious Disease Hospital of Tangshan,Tangshan 063000,China) |
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| Abstract: | Objective]To observe the efficacy of adefovir dipivoxil(ADV)combined with Fuzheng Huayu capsule for treating the chronic hepatitis B(CHB),and explore the influence on liver fibrosis.Methods]100 cases of patients with CHB were randomly divided into treatment group and control group.The control group received ADV treatment,and the treatment group combined with Fuzheng Huayu capsule.All patients received treatment for 1 year.The clinical efficacy was evaluated after the end of treatment.The serum liver fibro... |
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| Keywords: | Chronic hepatitis B Liver fibrosis Adefovir dipivoxil Fuzheng Huayu capsule |
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