奥美拉唑在幽门螺杆菌阳性的十二指肠球部溃疡治疗效果分析

目的观察奥美拉唑在幽门螺杆菌阳性的十二指肠球部溃疡治疗效果。方法 40例幽门螺杆菌阳性的十二指肠球部溃疡患者平分为两组,治疗组给予基于奥美拉唑的三联治疗方法,对照组给予基于埃索美拉唑的三联治疗方法。结果经过治疗后,治疗组总有效率为95.0%,对照组总有效率为75.0%,治疗组临床疗效明显好于对照组(P<0.05)。两组的Hp根除率分别为90.0%和75.0%,统计分析表明治疗组的根除率明显好于对照组(P<0.05)。两组不良反应情况对比无显著性差异(P>0.05)。结论奥美拉唑在幽门螺杆菌阳性的十二指肠球部溃疡治疗效果好,Hp根除多,安全性好,值得推广应用。

The Effect Analysis of Omeprazole in Helicobacter Pylori-positive Duodenal Ulcer Treatment

Objective To observe the effect of omeprazole in helicobacter pylori-positive duodenal ulcer treatment.Methods 40 patients with helicobacter pylori-positive duodenal ulcer were equally divided into two groups,the treatment group received omeprazole-based triple therapy,the control group received esomeprazole-based triple therapy.Results After the treatment,the total effective rate was 95.0% in the treatment group,the total effective rate was 75.0% in the control group,the clinical efficacy of the treatment group was significantly better than the control group(P <0.05).Hp eradication rate was 90.0% and 75.0% in the treatment group and the control group,the statistical analysis showed that the eradication rate in the treatment group was significantly better than the control group(P <0.05).There was no significant difference in adverse reactions of two groups(P >0.05).Conclusion Omeprazole in helicobacter pylori-positive duodenal ulcer treatment has good effect,more safet in Hp eradication rate,which is worthy of wide application.