| 451例药物不良反应报告分析 |
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| 引用本文： | 瞿敏. 451例药物不良反应报告分析[J]. 临床医学工程, 2011, 18(3) |
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| 作者姓名： | 瞿敏 |
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| 作者单位： | 瞿敏 (上海市宝山区大场医院,上海,200436) ； |
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| 摘 要： | 目的了解医院药品不良反应(ADR)发生的特点。方法对医院2006～2010年451例药品不良反应报告,分别从患者性别、药品种类、微生物出现次数、给药途径以及ADR累及器官或系统及临床表现等方面进行回顾性统计、分析。探讨和分析药物不良反应发生的各种因素。结果 451例药物不良反应中,女性占总例数的58.09%(262例);以静脉滴注方式给药引起的不良反应占总例数的87.36%(394例);最易引起不良反应的药品为抗感染药,占总例数的71.4%(322例);最常见的临床表现为皮肤及其附件损害,占总例数的62.75%(283例)。结论增强对药物不良反应的防范意识,采取必要的预防措施、应加强不良反应监测报告工作,尽可能减少或避免不良反应的发生。
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| 关 键 词： | 药物不良反应 不良反应报告 分析 |
Analysis of 451 ADR Cases Report |
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| Abstract: | Objective To investigate the characteristics of hospital adverse drug reaction (ADR) occurrence.Method 451 ADR cases from 2006 to 2010 were analyzed in respect of patients' age and sex,route of administration,drug species and clinical manifestation.The adverse drug reactions were discussed and analyzed in a variety of factors.Results In 451 ADR cases,there were 262 (58.09%) female,and 394 (87.36%) were induced by intravenous drop infusion,322(71.4%) were related to anti-infectives.The most common clinical manifestations of damage were skin and its appendages,283 cases (62.75%) in 451cases.Conclusion ADR monitor work should be strengthened to avoid or reduce the incidence of ADR. |
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| Keywords: | Adverse drug reaction Adverse reaction reports Analysis |
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