| Institution: | 1. Sheffield Haemophilia and Thrombosis Centre, Sheffield, UK;2. Laboratory Corporation of America Holdings, Burlington, NC, USA;3. Melbourne, Australia;4. Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway
Norwegian Organization for Quality Improvement of Laboratory Examinations (Noklus), Haraldsplass Deaconess Hospital, Bergen, Norway;5. Section of Clinical Biochemistry, University of Verona, Verona, Italy;6. Research Department of Haematology, University College London, London, UK;7. Department of Pathology, University of New Mexico, Albuquerque, NM, USA;8. Christian Medical College, Vellore, India |
| Abstract: | This guidance document has been prepared on behalf of the International Council for Standardisation in Haematology (ICSH). The aim of the document is to provide guidance and recommendations for collection of blood samples for coagulation tests in clinical laboratories throughout the world. The following processes will be covered: ordering tests, sample collection tube and anticoagulant, patient preparation, sample collection device, venous stasis before sample collection, order of draw when different sample types need to be collected, sample labelling, blood-to-anticoagulant ratio (tube filling) and influence of haematocrit. The following areas are excluded from this document, but are included in an associated ICSH document addressing processing of samples for coagulation tests in clinical laboratories: sample transport and primary tube sample stability; centrifugation; interfering substances including haemolysis, icterus and lipaemia; secondary aliquots—transport and storage; and preanalytical variables for platelet function testing. The recommendations are based on published data in peer-reviewed literature and expert opinion. |
