Involucrin expression in adnexal skin tumours |
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Authors: | J. Kanitakis G. Zambruno J. Viac J. Thivolet |
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Affiliation: | (1) Inserm U. 209 - Clinique Dermatologique, Hôpital Edouard Herriot, F-69437 Lyon Cedex 03, France |
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Abstract: | Summary The expression of involucrin was studied in a group of skin neoplasms, mostly of adnexal origin. As happens with other types of epithelial tumours, involucrin was detected in the most differentiated areas (presenting a squamoid or ductal differentiation). No reactivity was observed in non-epithelial skin tumours. These results suggest that involucrin is a specific marker for epithelial and adnexal differentiation of skin tumours and may thus be a useful aid in histopathologic diagnosis and classification of neoplasms. |
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Keywords: | Involucrin Adnexal skin tumours |
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