纤维蛋白封闭剂用于食管癌手术的临床分析

目的:探讨纤维蛋白封闭剂在食管癌根治术中的应用价值。方法:将食管癌患者62例,分为用胶组(27例)和未用胶组(35例),用胶组行常规食管癌根治术同时在手术创面应用纤维蛋白封闭剂,通过观察术后第12、24及48小时的胸腔闭式引流量及术后总引流量来确定纤维蛋白封闭剂在食管癌根治术中的有效性。结果:用胶组术后第12、24及48小时的胸腔闭式流量及术后总引流量均少于未用胶组,差异具有非常显著性(P<0.01)。结论:食管癌根治术中应用纤维蛋白封闭剂可以有效减少术后引流量,提早拔除胸腔闭式引流管,有利于患者的术后恢复。

Clinical Analysis of Using Fibrin Sealant during Perioperative Period

ABSTRACT: Objective To study on effectiveness of using fibrin sealant in radical surgery of esophageal carcinoma. Methods 62 patients with esophageal carcinoma were divided into fibrin sealant group(n=27) and non fibrin sealant group(n=35). Fibrin sealant was pasted to surgery area in fibrin sealant group. Drainage volumes of chest tube at 12th hour, 24th hour, 48th hour after surgery and total drainage volumes were compared in order to evaluate effectiveness of using fibrin sealant in radical surgery of esophageal carcinoma. Results Compared with non fibrin sealant group, drainage volumes in fibrin sealant group are significantly decreased at 12th hour, 24th hour, 48th hour after surgery and total drainage volumes are also significantly decreased(P<0.01). Conclusion Application of fibrin sealant in radical surgery of esophageal carcinoma can decrease drainage volume and make chest tube pulled out earlier after surgery, which is beneficial to recovery after surgery. KEY WORDS: fibrin sealant; esophageal neoplasm; operation