| 微波辐射对小白鼠脂质过氧化作用及神经递质含量的影响 |
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| 引用本文： | 曹兆进,张洪桥,陶勇,刘景兰,李双黎,徐培基,陈健. 微波辐射对小白鼠脂质过氧化作用及神经递质含量的影响[J]. 卫生研究, 2000, 29(1): 28-29 |
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| 作者姓名： | 曹兆进 张洪桥 陶勇 刘景兰 李双黎 徐培基 陈健 |
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| 作者单位： | 1. 中国预防医学科学院环境卫生监测所,北京,100021
2. 航天医学工程研究所 |
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| 基金项目： | 卫生部科技开发研究课题 |
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| 摘 要： | 用900MHz 微波连续照射雄性LACA 小白鼠,辐射强度分别为0、1、2和5m W/cm 2,比吸收率(SAR)分别为0、0.22、0.44和1.10W/kg,每天照射1小时,连续35天。结果发现,在电磁辐射强度为1m W/cm 2 时能引起小白鼠全血中谷胱甘肽过氧化物酶(GSH-Px)活性降低,丙二醛(MDA)含量增高,GSH-Px/MDA 比值降低,大脑去甲肾上腺素含量增高。辐射强度为2和5m W/cm 2 时未见上述生物学指标有显著性改变。大脑中单胺类神经递质5-羟色胺、5-羟吲哚乙酸和多巴胺的含量在各暴露组均未发现显著性变化
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| 关 键 词： | 微波 脂质过氧化 谷胱甘肽过氧化物酶 丙二醛 神经递质 |
Effects of microwave radiation on lipid peroxidation and the content of neurotransmitters in mice |
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| Cao Zhaojin,Zhang Hongqiao,Tao Yong,Liu Jinglan,et al.. Effects of microwave radiation on lipid peroxidation and the content of neurotransmitters in mice[J]. Journal of hygiene research, 2000, 29(1): 28-29 |
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| Authors: | Cao Zhaojin Zhang Hongqiao Tao Yong Liu Jinglan et al. |
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| Affiliation: | Institute of Environmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing 100021, China. |
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| Abstract: | Male LACA mice were exposed to 900MHz microwaves at the power densities of 0,1,2 and 5mW/cm 2.The resulting specific absorption rates(SARs) were 0,0 22,0 44 and 1 10W/kg respectively.Animals were exposed at the dosage of 1 hour a day for 35 days.The results showed that the activity of glutathione peroxidase(GSH Px) increased and the concentration of malondialdehyde(MDA) decreased in blood,and the concentration of noradrenaline(NE) increased in brains in the microwave exposed groups at 1mW/cm 2 compared with the sham exposed group.But no significant changes were found in the microwave exposed groups at 2 and 5mW/cm 2.No significant changes of the concentrations of 5 hydroxytryptamine(5 HT),5 hydroxyindole acetic acid(5 HIAA) and dopamie(DA) in brains were found. |
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| Keywords: | microwave lipid peroxidation glutathione peroxidase malondialdehyde neurotransmitter |
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