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不同幽门螺杆菌感染检测方法的评价
引用本文:董玲,孙剑勇,王吉耀. 不同幽门螺杆菌感染检测方法的评价[J]. 中国临床医学, 2003, 10(5): 645-646
作者姓名:董玲  孙剑勇  王吉耀
作者单位:复旦大学附属中山医院消化科,上海,200032
摘    要:目的:评价适合临床使用的检测幽门螺杆菌(Helicobacter pylori,Hp)的方法。方法:332例入选患者进行快速尿素酶,病理组织学,现症感染血清学抗体快速检测法(CIM-GLD’s Hp RT),3项中2项阳性认为有Hp感染。结果:CIM—GLD’s Hp RT,病理组织学,快速尿素酶法敏感性分别为95.77%、91.01%、81.48%;特异性分别为95.10%、96.so%、93.01%;阳性预测值分别为96.22%、97.18%、93.90%;阴性预测值分别为94.37%、89.03%、79.17%。结论:CIM-GLDs Hp RT具有较高的准确诊断HP感染的价值。

关 键 词:幽门螺杆菌感染 检测 评价 W—S染色 快速尿素酶

Evaluation Different Detecting Methods of Helicobacter Pylori Infection
Dong Ling Sun Jianyong Wang Jiyao. Evaluation Different Detecting Methods of Helicobacter Pylori Infection[J]. Chinese Journal Of Clinical Medicine, 2003, 10(5): 645-646
Authors:Dong Ling Sun Jianyong Wang Jiyao
Abstract:Objective: To seek a better diagnostic test for detecting Helicobacter pylori infection.Methods: 332 patients underwent endoscopy and biopsy. The speciments of gastric mucosa were tested by W-S stain, rapid urease tests (RUT), patients also had current infection marker Genelabs Hp rapid test (CIM-GLD's Hp RT). The presence of Hp infection was indicated by 2 positive of 3 tests.Results: The sensitivities were: CIM-GLD's Hp RT 95.77%, W-S stain 91.01%, RUT 81.48%; the specificity were: GLD's Hp RT 95.10%, W-S stain 96.50%, RUT 93.01%; the positive predictive values were: 96.22% , 97.18%, 93.90%; and the negative predictive values were: 94.37%, 89.03%, 79.17%.Conclusion: CIM-GLD's Hp RT is a more sensitive and accurate method for detecting Hp infection.
Keywords:Helicobacter pylori W-S stain Serological current infection marker rapid test Rapid urease test
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