耳穴贴压干预慢性支气管炎急性期的疗效观察

目的观察耳穴贴压干预慢性支气管炎急性期的临床疗效。方法将95例慢性支气管炎急性期患者随机分为对照组47例和观察组48例。两组均给予对症支持治疗,在此基础上观察组采用耳穴贴压干预。观察两组症状(喘息、咳嗽、湿啰音)消失及住院时间,治疗前后临床症状评分、肺功能指标[1 s用力呼气容积(FEV1)、用力肺活量(FVC)、FEV1/FVC]、血气分析指标[动脉血二氧化碳分压(PaCO2)、动脉血氧分压(PaO2)、动脉血氧饱和度(SaO2)]、睡眠质量指标(入睡时间、睡眠时间、睡眠效率、睡眠障碍)及血清炎症因子(CRP、IL-6、TNF-α)的变化,并比较两组临床疗效。结果两组临床疗效比较,差异有统计学意义(P<0.05)。观察组症状消失及住院时间较对照组短,差异均有统计学意义(P<0.05)。两组治疗后临床症状评分、肺功能指标、血气分析指标、PSQI评分及血清炎症因子水平与同组治疗前比较,差异均有统计学意义(P<0.05);观察组均优于对照组,差异均有统计学意义(P<0.05)。结论耳穴贴压可有效提高慢性支气管炎急性期患者的临床疗效,缓解症状,减少住院日,促进肺功能恢复,改善睡眠质量,降低机体炎症状态。

Therapeutic Observation of Auricular Point Sticking in Intervening Chronic Bronchitis in Acute Stage

Objective To observe the clinical efficacy of auricular point sticking in intervening chronic bronchitis in acute stage.Method A total of 95 patients with chronic bronchitis in acute stage were randomized into an observation group of 48 cases and a control group of 47 cases.The two groups were given symptomatic support treatment.In addition,the observation group was intervened by auricular point sticking.The durations of symptoms(shortness of breath,cough and moist rale)and hospital stay of the two groups were observed,as well as the post-treatment changes in clinical symptom score,pulmonary function indexes[forced expiratory volume in one second(FEV1),forced vital capacity(FVC)and FEV1/FVC],blood gas indexes(PaCO2,PaO2 and SaO2),sleep quality parameters(sleep latency,sleep duration,sleep efficiency and sleep disturbance)and serum inflammatory factors[C-reactive protein(CRP),interleukin(IL)-6 and tumor necrosis factor(TNF)-α].The clinical efficacy was also compared between the two groups.Result There was a significant difference in the clinical efficacy between the two groups(P<0.05).The durations of symptoms and hospital stay were shorter in the observation group than in the control group,and the differences were statistically significant(P<0.05).After treatment,the clinical symptom score,pulmonary function indexes,blood gas indexes,Pittsburgh Sleep Quality Index(PSQI)score and serum inflammatory factor levels changed significantly in both groups(P<0.05),and were better in the observation group than in the control group with statistical significance(P<0.05).Conclusion Auricular point sticking can effectively enhance the clinical efficacy in treatment of patients with chronic bronchitis in acute stage.It can release symptoms,shorten the hospital stay,boost the recovery of pulmonary function and improve sleep quality and inflammatory state.