阴道微生物芯片技术在阴道分泌物念珠菌检测中的应用

目的分析阴道微生物芯片检测技术在阴道分泌物样本念珠菌检测中的临床价值。方法收集233例疑似念珠菌性阴道炎患者的阴道分泌物样本,分别采用常规湿片镜检、真菌显色培养和阴道微生物芯片法进行检测,并对检测结果进行统计学分析。结果以真菌显色培养法为标准,常规湿片镜检法和阴道微生物芯片法的Kappa值分别为0.415和0.821,受试者工作特征(ROC)曲线下面积分别为0.73和0.91。结论阴道微生物芯片技术操作方便,报告及时、准确,对念珠菌性阴道炎的诊断具有较高的价值。

Application of vaginal microbial chip detection technique in the detection of vaginal secretion Candida

Objective To analyze the role of vaginal microbial chip detection technique in the detection of vaginal secretion Candida.Methods A total of 233 samples of vaginal secretion were collected.Routine microscopy,fungal culturing and vaginal microbial chip detection technique were performed.The results were analyzed statistically.Results The results of fungal culturing were used as gold standard,and the Kappa values were 0.415 and 0.821 by routine microscopy and vaginal microbial chip detection technique,respectively,and the areas under receiver operating characteristic(ROC)curves were 0.73 and 0.91,respectively.Conclusions The vaginal microbial chip detection technique is easy to operate,improves the efficiency of Candida detection in vaginal secretion samples,and has accuracy.It plays a role in timely and accurate diagnosis of Candida vaginitis.