上海市杨浦区居民中心型肥胖与心血管疾病危险因素及聚集性的关系

【目的】探讨上海市杨浦区居民中心型肥胖与心血管疾病危险因素及聚集性的关系,为制定心血管疾病预防控制措施和策略提供科学依据。【方法】以社区为单位,对35~75岁居民进行问卷调查、体格检查和血生化检测,对其中资料完整的11321人进行数据分析。【结果】杨浦区居民中心型肥胖率为60.50%,标化率为56.09%。不同腰围人群的收缩压、舒张压、空腹血糖、总胆固醇、三酰甘油、低密度脂蛋白和高密度脂蛋白的差异均有统计学意义(均P<0.01)。随着腰围的增加,高血压、糖尿病、血脂异常及心血管病危险因素聚集比例均呈上升趋势(均P<0.01)。多因素logistic回归结果显示,轻度、重度中心型肥胖组发生高血压、糖尿病、血脂异常和危险因素聚集的风险是正常组的1.78(OR=1.78,95%CI:1.63~1.94)和3.36倍(OR=3.36,95%CI:3.00~3.75)、1.67(OR=1.67,95%CI:1.49~1.88)和2.67倍(OR=2.67,95%CI:2.34~3.03)、1.68(OR=1.68,95%CI:1.54~1.82)和2.20倍(OR=2.20,95%CI:1.97~2.44)、2.04(OR=2.04,95%CI:1.86~2.24)和3.62倍(OR=3.62,95%CI:3.23~4.04)。【结论】上海市杨浦区居民中心型肥胖患病率高,肥胖程度与心血管疾病危险因素及其聚集风险有关,应当及时采取控制肥胖的干预措施。

Relationship between central obesity and cardiovascular disease risk factors and resident aggregation in Yangpu District,Shanghai

[Objective]To study the relationship between central obesity and cardiovascular disease risk factors and aggregation in Yangpu District,and to provide scientific basis for the prevention and control measures and strategies for cardiovascular disease.[Methods]In the community,residents aged 35 to 75 were investigated by questionnaire,physical examination and blood biochemical test,and a total of 11321 residents with complete data were analyzed.[Results]The prevalence of central obesity among adults in Yangpu was 60.50%(standardized rate was 56.09%).The level of systolic blood pressure,diastolic blood pressure,fasting blood glucose,total cholesterol,triglycerides,low-density lipoprotein and high-density lipoprotein were significantly different in different waist circumference groups(all P<0.01).With the increase of waist circumference,the prevalence of hypertension,diabetes,dyslipidemia,and cardiovascular risk factors clustering was increased(all P<0.01).Multivariable logistic regression results showed that the risk of hypertension,diabetes,dyslipidemia and cardiovascular risk factors clustering was 1.78(OR=1.78,95%CI:1.63-1.94)and 3.36(OR=3.36,95%CI:3.00-3.75);1.67(OR=1.67,95%CI:1.49-1.88)and 2.67(OR=2.67,95%CI:2.34-3.03);1.68(OR=1.68,95%CI:1.54-1.82)and 2.20(OR=2.20,95%CI:1.97-2.44);2.05(OR=2.04,95%CI:1.86-2.24)and 3.62 times(OR=3.6295%CI:3.23-4.04)fold higher in residents with mild and severe central obesity than those without central obesity.[Conclusion]The prevalence of central obesity among residents in Yangpu District of Shanghai is high,and the extent of central obesity is related to cardiovascular diseases risk factors and their aggregation.Therefore,timely intervention measures should be taken to control obesity.