1879例药品不良反应回顾分析

目的分析医院药品不良反应(ADR)发生规律和特点,为临床合理用药提供安全信息。方法对我院2006~2009年收集到的1 879例ADR报告分别从患者的年龄、性别、药品种类、给药途径、临床表现等方面进行统计分析。结果 1 879例ADR中,抗微生物类药物报告最多,占42.42%(797例),其次为中药制剂;给药途径以静脉给药为主。ADR累及的系统—器官以皮肤及其附件损害为主,其次是消化系统损害等。结论应加强ADR监测,特别是抗微生物药和中药注射液的监测,减少或避免药品不良反应的发生,确保用药安全。

Reviewing and analysis of 1879 cases of ADRs happened in our hospital

OBJECTIVE Analyse the regular pattern and characteristics of adverse drug reactions （ ADRs ） happened in our hospital,in order to provide clinical safety information for rational drug use. METHODS Analyse 1 879 cases of ADRs collected from the year 2006 to 2009 in our hospital, including the patients＇ age, gender, type of the drugs, route of administration and clinical manifestation. RESULTS In the 1 879 cases of ADRs reports, the most frequently happened were antimicrobial drugs, accounting for 42.42% （ 797 cases ） , the second was Chinese drugs pharmaceutics ; In the 1879 cases of ADRs intravenous administration was the main route of administration. Damage to skin and its appendages were the most common symptoms,digestive system injure was the second. CONCLUSION We should strengthen ADR monitoring, especially in the monitoring of the antimicrobial drug and the Chinese medicine injection, make our best efforts to reduce or prevent the occurrence of ADRs ,in order to insure the safety of drug use.