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加味五苓散合六味地黄汤对早期高血压肾损害的作用研究
引用本文:全毅红.加味五苓散合六味地黄汤对早期高血压肾损害的作用研究[J].首都医药,2011(8):44-46.
作者姓名:全毅红
作者单位:武汉市中心医院,430014
摘    要:目的观察中西药联用对早期高血压肾损害患者肾脏的保护作用,探讨高血压病早期肾损害的有效治疗方法。方法将65例符合标准的高血压病早期肾损害患者随机分为治疗组(35例)和对照组(30例)。两组患者均给予贝那普利片口服的基本治疗,治疗组另外给予加味五苓散合六味地黄汤;8周为一疗程,观察治疗前后的血压、尿微量白蛋白(micro-albumin,MA)、尿β2-微球蛋白(β2-MG)以及血生化指标的变化。结果治疗组不仅能明显降低血压,而且能显著降低尿微量白蛋白、尿β2-微球蛋白的排出量,疗效明显优于对照组(P〈0.01)。同时,治疗组的血脂降低,脂质代谢紊乱被纠正,血液黏稠度降低,血液流变学改善。结论健脾益肾、温阳化气、活血通络法是治疗高血压病早期肾损害的一种有效治法,加味五苓散合六味地黄汤是治疗高血压病早期肾损害的一组有效药物,对早期高血压肾损害患者的肾脏有很好的保护作用。

关 键 词:高血压病  肾损害  加味五苓散合六味地黄汤

Investigation of renal protective effect in early hypertensive renal injury by supplemented Wuling San combined with Liuweidihuang decoction
Quan Yihong.Investigation of renal protective effect in early hypertensive renal injury by supplemented Wuling San combined with Liuweidihuang decoction[J].Capital Medicine,2011(8):44-46.
Authors:Quan Yihong
Institution:Quan Yihong (The Central Hospital of Wuhan,Wuhan 430014,China)
Abstract:Objective To observe the effective treatment in early hypertensive renal injury, investigate the renal protective effect of integrated traditional chinese and western medicine. Methods 65 cases of early hypertensive renal injury were divided into treating group (35 cases) and control group (30 cases) randomly. They were all treated with benazepril, the treating group was given modified wuling san and liuweidihuang tang beside. The total cure was 8 weeks. Investigate the change of hypertension, micro-albumin...
Keywords:hypertension  renal injury  supplemented Wuling San combined with Liuweidihuang decoction  
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