| 人参总皂苷脂质体的制备及质量评价 |
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| 引用本文： | 陈新梅. 人参总皂苷脂质体的制备及质量评价[J]. 齐鲁药事, 2011, 30(2): 63-64 |
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| 作者姓名： | 陈新梅 |
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| 作者单位： | 山东中医药大学药学院,山东,济南,250355 |
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| 基金项目： | 山东省高等学校科技计划项目，山东中医药大学2009年SRT项目 |
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| 摘 要： | 目的制备人参总皂苷(TSPG)脂质体,并进行质量评价。方法采用薄膜分散法、逆相蒸发法、乙醇注入法制备TSPG脂质体,以形态、包封率、载药量为指标筛选制备方法。结果薄膜分散法制备的TSPG脂质体外形规则、光滑、不黏连,包封率、载药量分别为38.70%、3.14%,较其他方法好。结论薄膜分散法制备的TSPG脂质体达到预期目标。
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| 关 键 词： | 人参总皂苷 脂质体 质量评价 |
Preparation and quality evaluation of total saponins of panax ginseng liposomes |
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| CHEN Xin-mei. Preparation and quality evaluation of total saponins of panax ginseng liposomes[J]. qilu pharmaceutical affairs, 2011, 30(2): 63-64 |
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| Authors: | CHEN Xin-mei |
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| Affiliation: | CHEN Xin-mei(Shandong University of Traditional Chinese Medicine,Jinan 250355,China) |
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| Abstract: | Objective To prepare the total saponins of panax ginseng(TSPG) liposomes and evaluate their qualities.Methods Three different preparation method including film dispersion method,reverse-phase evaporation and ethanol infection method.TSPG liposomes were compared according to the appearance,encapsulation efficiency and drug loading.Results The shape of TSPG liposomes prepared by film dispersion method was spherical or similar to spherical,which was smooth and disconglutinated.The encapsulation efficiency was ... |
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| Keywords: | Total saponins of panax ginseng Liposomes Quality evaluation |
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