| 乌阳补心胶囊质量标准研究 |
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| 引用本文： | 冯景辉,孙大勇,李俊平,姜明章.乌阳补心胶囊质量标准研究[J].齐鲁药事,2011,30(2):91-93. |
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| 作者姓名： | 冯景辉 孙大勇 李俊平 姜明章 |
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| 作者单位： | 烟台大洋制药有限公司,山东,烟台,265500 |
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| 摘 要： | 目的建立乌阳补心胶囊的质量标准控制方法。方法采用薄层色谱法对本品中的何首乌、甘草、黄芪、淫羊藿进行薄层鉴别;采用高效液相色谱法对本品中的2,3,5,4′-四羟基二苯乙烯-2-O-β-D-葡萄糖苷进行含量测定。结果在薄层色谱图中可检出何首乌、甘草、黄芪、淫羊藿;2,3,5,4′-四羟基二苯乙烯-2-O-β-D-葡萄糖苷在0.116~2.32μg范围内呈良好的线性关系(r=0.999 8),平均回收率为100.40%,RSD=0.64%。结论所建立的方法可靠、准确、专属性强,可有效控制乌阳补心胶囊的质量。
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| 关 键 词： | 质量标准 2 3 5 4′-四羟基二苯乙烯-2-O-β-D-葡萄糖苷 乌阳补心胶囊 高效液相色谱法 薄层色谱法 |
Study on quality standard for Wuyangbuxin Capsules |
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| FENG Jing-hui,SUN Da-yong,LI Jun-ping,JIANG Ming-zhang.Study on quality standard for Wuyangbuxin Capsules[J].qilu pharmaceutical affairs,2011,30(2):91-93. |
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| Authors: | FENG Jing-hui SUN Da-yong LI Jun-ping JIANG Ming-zhang |
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| Institution: | (Yantai Dayang Pharmaceutical Co.,Ltd.,Yantai 265500,China) |
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| Abstract: | Objective To establish the quality standard for Wuyangbuxin Capsules.Methods The Polygonum multiflorum Thunb.,Glycyrrhiza uralensis Fisch.,Astragalus membranaceus（Fisch.）Bge.var.Mongholicus（Bge.）Hsiao,Epimedium brevicornum Maxim in Wuyangbuxin Capsules were identified by TLC;The content of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside was dentermined by HPLC.Results The Polygonum multiflorum,Glycyrrhiza uralensis,Astragalus membranaceus and Epimedium were detected in TLC chromatogram.The linear range of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside was 0.116 ～2.32 μg（r=0.999 8）,and the average recovery was 100.40% with RSD=0.64%（n=5）.Conclusion The method was reliable,accurate and specifie,and can effectively control the quality of Wuyangbuxin Capsules. |
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| Keywords: | Quality standard 2 3 5 4′-Tetrahydroxystilbene-2-O-β-D-glucoside Wuyangbuxin Capsules HPLC TLC |
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