人工耳蜗植入者失匹配负波的特征研究

目的初步研究人工耳蜗植入者在言语声刺激下引出失匹配负波(mismatch negativity,MMN)的波形表现及相关意义。方法 采用经典Oddball模式,以/ba/和da/的言语声为标准刺激和偏差刺激,测量人工耳蜗植入组及正常对照组MMN,分析2组受试者MMN潜伏期及波幅、言语识别得分及平均听阈的相关性。结果 人工耳蜗植入组与正常对照组MMN潜伏期差异具有统计学意义,而波幅差异无统计学意义。人工耳蜗植入组中,言语识别得分与MMN潜伏期及波幅相关性有显著意义。结论 M MN潜伏期、波幅均与言语识别得分相关性显著,即可作为一项客观检查,为判断人工耳蜗植入后患者言语识别能力提供客观依据。

Analysis of Mismatch Negativity in Cochlear Implant Users

Objective To investigate the characteristics of the cochlear implant users on mismatch negativity(MMN).
Methods The standard(/ba/) and deviant stimuli (/da/) were presented in an oddball paradigm and the MMN were recorded. The relevance among the scores of speech discrimination and the characters of MMN and the mean auditory thresholds were investigated.
Results The peak latency of MMN in the cochlear implant(CI) group was significantly longer than that in the control group, but the amplitude changed slightly. A significant correlation was found between the scores of speech discrimination and the characters of MMN in CI group.
Conclusion There was significant correlation among the scores of speech discrimination and MMN, which further confirmed that mismatch negativity is a tool for the assessment of stimuli discrimination in cochlear implant subjects.