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沙利度胺联合MP及VAD方案治疗多发性骨髓瘤42例
引用本文:王贵锋.沙利度胺联合MP及VAD方案治疗多发性骨髓瘤42例[J].中国医药导报,2010,7(28):59-60.
作者姓名:王贵锋
作者单位:河南省开封市第二人民医院血液科,河南开封,475002
摘    要:目的:探讨沙利度胺联合MP及VAD方案治疗多发性骨髓瘤的疗效。方法:对应用沙利度胺联合MP及VAD方案治疗的42例患者的临床资料进行回顾性分析。结果:初治病例32例给予沙利度胺联合MP方案治疗,总有效率为81.2%;复发病例10例给予沙利度胺联合VAD方案治疗,总有效率为80.0%。结论:沙利度胺联合MP及VAD方案治疗多发性骨髓瘤具有缓解率优于以往的常规(MP或VAD方案)治疗,且副作用少,患者耐受性好,疗效确切。

关 键 词:多发性骨髓瘤  联合化疗  沙利度胺

Thalidomide combined with MP and VAD in the treatment of multiple myeloma for 42 cases
WANG Guifeng.Thalidomide combined with MP and VAD in the treatment of multiple myeloma for 42 cases[J].China Medical Herald,2010,7(28):59-60.
Authors:WANG Guifeng
Institution:WANG Guifeng (Department of Hematology, the Second People's Hospital of Kaifeng City, He′nan Province, Kaifeng 475002, China)
Abstract:Objective: To discuss the clinical efficacy of the Thalidomide combined with MP and VAD in the patients with multiple myeloma. Methods: Clinic data of 42 patients with multiple myeloma used Thalidomide combined with MP and VAD were analyzed retrospectively. Results: 32 with multiple myeloma in first-time treatment group were given Thalidomide combined with MP, the total effective rate was 81.2%; 10 cases with multiple myeloma in relapse group were given Thalidomide combined with VAD, the total effective rate was 80.0%. Conclusion: Thalidomide combined with MP and VAD in the treatment of multiple myeloma were better than that of conventional therapy scheme (MP or VAD), and less side effects, good tolerance of patients or certain efficacy.
Keywords:Multiple myeloma  Combined chemotherapy  Thalidomide
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