| 增生性玻璃体视网膜病变及蛋白质组学研究 |
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| 引用本文： | 周庆芸,张学东.增生性玻璃体视网膜病变及蛋白质组学研究[J].眼科研究,2010,28(1):93-96. |
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| 作者姓名： | 周庆芸 张学东 |
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| 作者单位： | 重庆医科大学附属第一医院眼科,400016 |
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| 摘 要： | 增生性玻璃体视网膜病变（PVR）是一种复杂的多因素作用的致盲性眼病，与视网膜脱离、糖尿病视网膜病变（DR）等疾病密切相关。蛋白质组学是研究细胞或机体中全部蛋白质组成及其变化规律的科学，并能在大分子水平获得对疾病的发病机制和过程等方面新的认识。对PVR的发病机制及其在蛋白质组学方面的研究进展进行综述。
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| 关 键 词： | 增生性玻璃体视网膜病变 蛋白质组学 视网膜脱离 糖尿病视网膜病变 |
Current progress in proteomics research of proliferative vitreoretinopathy |
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| Zhou Qingyun,Zhang Xuedong.Current progress in proteomics research of proliferative vitreoretinopathy[J].Chinese Ophthalmic Research,2010,28(1):93-96. |
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| Authors: | Zhou Qingyun Zhang Xuedong |
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| Institution: | Zhou Qingyun,Zhang Xuedong.( Affiliated First Hospital of Chongqing Medical University, Chongqing 400016, China) |
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| Abstract: | Proliferative vitreoretinopathy (PVR)is a serious causing-blindness disease.It is intimately associated with retinal detachment (RD),proliferative diabetic retinopathy (PDR)and penetrating ocular injury with the complicated course and aggravating outcome.Proteomics is a science about investigating the total proteins in cellular level or organism level.The study of proteomics is helpful for reinforcing the cognition and understanding of pathogenesis and development of PVR.So proteomics study about PVR is becoming a new topic.The study progress in the mechanism of PVR,the study background and technique of proteomics,the application of proteomics study in PVR and relative ocular diseases mentioned above are reviewed in this paper. |
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| Keywords: | proliferative vitreoretinopathy proteomics retinal detachment proliferative diabetic retinopathy |
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