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吡贝地尔治疗帕金森病的临床研究
引用本文:闫卫红,程焱.吡贝地尔治疗帕金森病的临床研究[J].中西医结合心脑血管病杂志,2005,3(10):853-855.
作者姓名:闫卫红  程焱
作者单位:[1]山西医科大学第一医院,030001 [2]天津医科大学总医院,030001
摘    要:目的观察吡贝地尔治疗帕金森病的临床疗效.方法对50例帕金森病病人行统一评分量表(UPDRS)评分,8例新发病人未服用任何抗帕金森病药物治疗者即予吡贝地尔治疗,其余病人在原用药的基础上加用吡贝地尔.用药12周后,再次行UPDRS量表评分,比较吡贝地尔治疗前后UPDRS量表分值的差异.结果 50例病人经吡贝地尔治疗后,有效35例,有效率为72.9%.治疗前后UPDRS总评分、Ⅱ分量表、Ⅲ分量表评分和震颤、肌强直症状改善评分的结果均有统计学意义.结论吡贝地尔可有效改善帕金森病病人的临床症状.

关 键 词:吡贝地尔  帕金森病  统一评分量表  震颤  肌强直
文章编号:1672-1349(2005)10-0853-03
收稿时间:2005-08-15
修稿时间:2005年8月15日

Therapeutic Effect of Piribedil in Parkinson's Disease
Yan Weihong, Chen Yan,.Therapeutic Effect of Piribedil in Parkinson''''s Disease[J].Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease,2005,3(10):853-855.
Authors:Yan Weihong  Chen Yan  
Institution:Neurology Department, The First Hospital, Shanxi Medical University,Taiyuan 030001
Abstract:Objective To study the therapeutic effect of piribedil in Parkinson's disease.Methods Fifty patients (pts) with Parkinson's disease were treated with piribedil for 12 weeks and evaluated with UPDRS table pre-and post-therapy.Results Following the therapy of piribedil, the symptom of Parkinson's disease alleviated in 35 pts significantly. The value of UPDRS improved significantly.Conclusion The results suggest that there is significant therapeutic effect of piribedil for Parkinson's disease.
Keywords:piribedil  Parkinson's disease  UPDRS table  tremor  rigidity
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