新生儿金黄色葡萄球菌败血症167例临床分析

本科１９９２年３月至１９９３年２月收治新生儿金黄色葡萄球菌败血症１６７例，占同期新生儿败血症（血培养阳性）之首位。感染途径为呼吸道（３７．１％）、脐部（３５．２％）及皮肤（８．３％）。新生儿金黄色葡萄球菌败血症特点：（１）感染中毒症状可以不重；（２）约半数合并肺炎（大多为轻型），脓胸、脓气胸、肺脓肿等少见；（３）猩红热样皮疹、多形性皮疹少见；（４）外周血白细胞计数以增高为主，Ｉ／Ｔ增高不多见，血小板减少多见。

CLINICAL ANALYSIS OF 167 CASES OF NEONATALSTAPHYLOCOCCUS AUREUS SEPTICEMIA

Analysis of 167 cases of neonatal staphylococcus aureus septicemia admitted during March 1992 to February 1993 was reported in this paper.Staphylococcus aureus was the major pathogen(37%)of neonatal septicemia with positive blood culture during this period. The respiratory tract(37.1%),navel(35.2%)and skin(8.3%)were the main invasive routes by the bacteria. Their clinical characteristics are as follows:(1)mild toxic symptoms;(2)almost one half of the cases complicated with pneumonia, while empyema, pyopneumothorax and lung abscess are less common;(3)scarlatinoid rashes and polymorphic eruption are rare; and(4)peripheral blood examinations show leukocytosis in majority of the babies, and the rise of I/T ratio is uncommon and thrombocytopenia is seen frequently.