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卵巢早衰的病因探讨
引用本文:蒋月英,张治芬,周馥贞,姚芷芳,李蕴芝,宋伊丽.卵巢早衰的病因探讨[J].浙江大学学报(医学版),1992(1).
作者姓名:蒋月英  张治芬  周馥贞  姚芷芳  李蕴芝  宋伊丽
作者单位:浙江医科大学附属妇产科医院内分泌组,浙江医科大学附属妇产科医院内分泌组,浙江医科大学附属妇产科医院内分泌组,浙江医科大学附属妇产科医院内分泌组,浙江医科大学附属妇产科医院内分泌组,浙江医科大学附属妇产科医院B超室
摘    要:本文对96例卵巢早衰(POF)患者进行了病因探讨,经有关检查提示,家族倾向、染色体异常和卵巢发育不全导致原始生殖细胞数少或缺乏可能为POF的主要原因;其次为生殖细胞遭受各种因素破坏和通过免疫机制使滤泡加速闭锁.

关 键 词:卵巢早衰/病因学  卵巢疾病/病因学

ETIOLOGICAL RESEARCH OF PREMATURE OVARIAN FAILURE
Jiang Yueying, Zhang Zhifen, Zhou Fuzhen Affiliated Hospital of Obstetrics and Gynecology.ETIOLOGICAL RESEARCH OF PREMATURE OVARIAN FAILURE[J].Journal of Zhejiang University(Medical Sciences),1992(1).
Authors:Jiang Yueying  Zhang Zhifen  Zhou Fuzhen Affiliated Hospital of Obstetrics and Gynecology
Institution:Jiang Yueying; Zhang Zhifen; Zhou Fuzhen Affiliated Hospital of Obstetrics and Gynecology
Abstract:The etiological cause of 96 patients with premature ovarian failure was analyzed. The result suggested that the main cause of premature ovarian failure might be the deficiency or decrease in the number of primordial germ cells, which results from genetic disposition, chromosomal abnormalities and ovarian dysgenesis. The second factor might be the destruction of germ cells by various causes and the acceleration of the follicle atresia through an autoimmune mechanism.
Keywords:Premature ovarian failure/etiol  Ovarian diseases/etiol  
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