三羊益心康胶囊对麻醉犬血流动力学和心肌耗氧量的影响

目的:观察三羊益心康胶囊对麻醉犬血流动力学和心肌耗氧量的影响。方法:采用麻醉犬在体心脏实验法,经十二指肠给予三羊益心康胶囊,于给药后不同时间点测定血流动力学和心肌耗氧量各项参数。结果:三羊益心康胶囊能明显增加麻醉犬冠脉血流量、心输出量、心搏出量、心脏指数、心搏指数,降低总外周阻力和冠状动脉阻力,减少心肌耗氧量、心肌耗氧指数及心肌氧摄取率。结论:三羊益心康胶囊能明显改善麻醉犬血流动力学,降低心肌耗氧量。

Effect of SanyangYisinkang Capsule on the Cardiohemodynamics and Myocardial Oxygen Consumption in Anesthetized Dogs

Objective:To study the effect of Sanyang Yisinkang Capsule on the cardiohemodynamics and myocardial oxygen consumption in anesthetized dogs.Methods: Expermental technology of in vivo heart of anestheticzed dogs was adopted.After Sanyang Yisinkang Capsule was administrated to the anestheticzed dogs through duodenum,the parameters of hemodynamice and oxygen consumption were determined at different times Results:The coronary flow,cardiac output,stroke volume,cardiac index,stroke index were increased,total peripheral resistance,resistance arteria coranaria were degraded and oxygen consumption of myocardium,oxygen consumption index,the cardiac muscle uptake rate were decreased.Conclusion:Sanyang Yisinkang Capsule can improve the cardiohemodynamics and myocardial oxygen consumption in anesthetized dogs.