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非酒精性脂肪性肝病药物治疗进展
引用本文:蒋艳明,施军平.非酒精性脂肪性肝病药物治疗进展[J].临床肝胆病杂志,2011,27(9):986-990.
作者姓名:蒋艳明  施军平
作者单位:1. 浙江中医药大学,杭州,310053
2. 浙江中医药大学附属杭州第六医院中西医结合科,杭州,310014
基金项目:浙江省中医药计划科技项目
摘    要:非酒精性脂肪性肝病(NAFLD)是我国肝酶异常和慢性肝病的常见原因之一,其治疗包括控制饮食、运动锻炼和药物治疗。目前,临床上治疗NAFLD的药物包括减肥药、胰岛素增敏剂、抗氧化剂、抑制肾素血管紧张素系统的降压药、调脂药、细胞因子调节剂和具有良好前景的大麻素受体拮抗剂。在此对NAFLD治疗药物的近期发展作一综述。

关 键 词:脂肪肝  减肥药  二甲双胍  噻唑烷二酮类  受体  大麻酚  己酮可可碱

The progress of pharmacotherapy in non- alcoholic fatty liver disease
JIANG Yan-ming,SHI Jun-ping.The progress of pharmacotherapy in non- alcoholic fatty liver disease[J].Chinese Journal of Clinical Hepatology,2011,27(9):986-990.
Authors:JIANG Yan-ming  SHI Jun-ping
Institution:.(Zhejiang Traditional Chinese Medicine University,Hangzhou 310053,China)
Abstract:Non-alcoholic fatty liver disease is one of the common reasons of chronic liver disease and leading liver enzyme abnormally in china.The treatment for NAFLD includes diet control,exercise and pharmacotherapy.At present,the drugs for NAFLD used in clinic include diet pill,insulin sensitizer,antioxidant,antihypertensive drug for suppressing the renin-angiotensin system,lipid-lowering drugs,cytokines-regulator agents the promising agent cannabinoid receptors antagonists.We will review the recent advances about the pharmacotherapy in non-alcoholic fatty liver disease here.
Keywords:fatty liver  anti-obesity agents  metformin  thiazolidinediones  receptors  cannabinoid  pentoxifylline
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