治疗小儿毛细支气管炎4种不同方案的成本-效果分析

目的：评价治疗小儿毛细支气管炎4种不同方案的药物经济学效果。方法：运用药物经济学成本-效果分析法对利巴韦林静脉滴注组（A组）、炎琥宁静脉滴注组（B组）、双黄连静脉滴注组（C组）、莪术油葡萄糖静脉滴注组（D组）4种治疗方案进行回顾性分析评价。结果：4组治愈率分别为34.4%、75.7%、43.0%、76.7%（χ^2=49.04,P〈0.01）,成本分别为1 334.84±386.40元、1 505.36±347.39元1、463.60±487.87元、1 196.76±366.74元,成本-效果比分别为38.80±11.23元、19.89±4.59元、34.04±11.35元、15.60±4.78元。结论：治疗小儿毛细支气管炎疾病,以选用D组或B组治疗方案为宜。

Cost-Effectiveness Analysis of Four Different Therapeutic Schemes in Treating Acute Bronchiolitis in Children

OBJECTIVE： To evaluate the pharmacoeconomic effects of four different therapeutic schemes in the treatment of acute bronchiolitis in children. METHODS ： The cost - effectiveness analysis was carried out on four therapeutic schemes in the treatment of acute bronchiolitis in children： Ribavirin （Group A ）, Potassium Sodium Dehydroandrographolide Succinate （Group B）, Compound Coptide （Group C）, and Zedoary Turmeric oil and Glucose （Group D）. All the drugs were administered by intravenous infusion. RESULTS ： The cure rates of the four groups were 34.4 %, 75.7 %, 43.0 % and 76.7 % （ x^2 = 49.04, P 〈 0.01 ） respectively ; the costs were （ 1 334.84 ± 386.40）, （ 1 505.36 ± 347.39）, （ 1 463.60 ± 487.87） and （ 1 196.76 ± 366.74） Yuan; the cost - effectiveness ratios were （38.80 ± 11.23）, （ 19.89 ± 4.59）, （34.04 ± 11 . 35） and （ 15.60 ± 4.78） respectively. CONCLUSION ： Group D or Group B were the preferable schemes for acute bronchiolitis in children.