大黄酸肠溶片的制备 |
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引用本文: | 童敏,谭梅英,朱永坤,詹利之. 大黄酸肠溶片的制备[J]. 海峡药学, 2016, 0(6): 7-9. DOI: 10.3969/j.issn.1006-3765.2016.06.003 |
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作者姓名: | 童敏 谭梅英 朱永坤 詹利之 |
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作者单位: | 1. 东莞市第三人民医院 东莞 523326;2. 广东省第二中医院 广州510095;3. 广州中医药大学青蒿研究中心广州510405 |
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摘 要: | 目的:研制大黄酸肠溶片。方法采用正交试验设计法,以包衣效率为指标,考察雾化压力、蠕动泵转速、枪床距离3个因素,优化大黄酸肠溶片的包衣工艺。结果最佳工艺参数,雾化压力4.5kg/cm2、蠕动泵转速1.5mL? min -1、枪床距离30cm。结论所制备的肠溶片符合设计要求,适合临床应用。
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关 键 词: | 大黄酸 肠溶片 制备工艺 |
Preparation of Rhein enteric Coated TabIets |
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Abstract: | OBJECTIVE To study the preparation of rhein enteric coated tablets .METHODS Orthogonal ex-periment design was used to optimize the process of preparation , and atomization pressure , peristaltic pump speed , distance between spray gun and pan were investigated .RESULTS The optimal technical conditions were as fol-lows:atomization pressure 4.5kg/cm2 ,peristaltic pump speed 1.5mL? min -1 ,distance between spray gun and pan 30 cm.CONCLUSION The enteric coated tablets comply with the design requirement ,and suitable for clinical ap-plication. |
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Keywords: | Rhein Enteric coated tablets Preparation technology |
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