沈阳市呼吸道合胞病毒肺炎住院患儿药物使用情况分析

目的 了解辽宁省沈阳市呼吸道合胞病毒肺炎住院患儿的药物使用情况，为进一步评价临床合理用药提供参考依据。方法 收集沈阳市某4所三级甲等医院2012年3月-2014年9月收治的372例≤6周岁呼吸道合胞病毒肺炎住院患儿的病历资料，分析其药物使用情况。结果 372例呼吸道合胞病毒肺炎住院患儿中，抗菌药物使用率为97.33%，抗病毒药物使用率为54.84%；患儿共使用抗菌药物32种、抗病毒药物9种，合计7类药物1 254例次，其中使用头孢菌素类抗菌药物608例次，占48.5%；使用抗病毒类药物258例次，占20.6%；使用大环内酯类抗菌药物183例次，占14.6%；使用青霉素类抗菌药物139例次，占11.1%；使用氨基苷类抗菌药物35例次，占2.8%；使用磺胺类抗菌药物30例次，占2.4%；使用喹诺酮类抗菌药物1例次，占0.1%。结论 沈阳市呼吸道合胞病毒肺炎住院患儿以使用抗菌药物治疗为主，抗病毒药物使用不足。

Medication status among hospitalized children with respiratory syncytial virus pneumonia in Shenyang city

Objective To study the status of medication among child patients hospitalized due to respiratory syncytial virus pneumonia in Shenyang city,Liaoning province and to provide evidences for evaluating reasonable clinical drug application.Methods Medical records of 372 children aged 6 years and younger diagnosed with respiratory syncytial virus pneumonia and hospitalized between March 2012 and September 2014 were extracted from 4 tertiary hospitals of grade A in Shenyang city to analyze drug use among the child patients.Results Of the patients,97.33% (362/372)were treated with 32 types of antibiotics and 54.84% (204/372)with 9 types of antiviral drugs.The total number of antimicrobial and antiviral regimens applied to the child patients was 1 254 person times and the regimens involved 7 categories of antibiotics and antiviral drugs,including cephalosporin antibiotics (608 person times,accounting for 48.48% of all the medication regimens),antiviral drugs (258,20.6%),macrolide antibacterial drugs (183,14.6%),penicillin antibiotics drugs (139,11.1%),aminoglycoside antibacterial drugs (35,2.8%),sulfonamides antibacterial drugs (30,2.4%),and quinolone antibacterial drugs (1,0.1%).Conclusion Antibiotics are the most commonly used drugs and antiviral medication is not used enough among hospitalized children with respiratory syncytial virus pneumonia in Shen-yang city.