开颅术后颅内感染的危险因素及防治措施

目的探讨颅脑手术后颅内感染的危险因素及防治方法。方法对我院1952例颅脑手术后66例发生颅内感染患者的临床资料进行了回顾性分析。结果66例开颅术后颅内感染者，61例颅内感染得到控制，4例死亡，1例自动出院。结论急症、后颅窝手术、脑脊液漏、脑室外引流及手术时间过长为术后发生颅内感染的高危因素，严格的无菌操作、开展微创手术、围手术期使用有效抗生素以及针对不同的危险因素采取相应的预防措施可减少术后颅内感染的发生，正确用药对控制颅内感染效果较好。

Risk Factors Related to Intracranial Infection after Craniotomy and Mseasures to Prevent and Treat It

Objective To investigate the risk factors relaterd to the intracranial infection after the craniotomy and the measures to prevent and treat it. Method The clinical data of 66 patients with postoperative intracranial infection in 1 952 patients undergoing the craniotomy from Janury, 2003 and April, 2008 were analysed retrospectively. Results Of 66 patients with intracranial infection after the craniotomy, 61 were cured, 4 died and 1 gave up treatment and was voluntarily dischaenged from hospital. Conclusions The risk factors related to the postoperative intracranial infection include the emergent operation, operation at the posterior cranial fossa, leakage of cerebroaspinal fluid, drainage outside the ventrcle, too long duration of the operaton and so on. The measures to prevent the intracranial infection after the craniotomy include strict aseptic technique, minimally invasive surgery, use of effective antibiotics in the periopertive period and so on. The curative effect of correct use of antibiotics on the intraeranial infection after the craniotomy is good.