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| 干姜挥发油提取优化及GC-MS图谱研究 | |
| 引用本文： | 李翔,吴豪,朱东亮,柴逸峰,娄子洋. 干姜挥发油提取优化及GC-MS图谱研究[J]. 药学实践杂志, 2009, 27(1): 46-48,50 |
| 作者姓名： | 李翔 吴豪 朱东亮 柴逸峰 娄子洋 |
| 作者单位： | 1. 第二军医大学药学院药物分析教研室,上海,200433;北京军区疾病预防控制中心,北京,100042 2. 第二军医大学药学院药物分析教研室,上海,200433 3. 第二军医大学药学院分析测试中心,上海,200433 |
| 摘 要： | 目的:优化千姜挥发油提取工艺,同时建立干姜挥发油GC-MS指纹图谱.方法:以挥发油得率为指标,采用正交设计,对加水量、超声时间、浸泡时间和提取时间进行优化,并采集GC-MS图谱.结果:确定加17倍量水,超声35 min,浸泡40 min,再提取8 h的效果最优,挥发油得率分别为1.89%,GC-MS图谱稳定、重复.结论:干姜挥发油经过提取优化可以保证得率,获得的GC-MS图谱稳定可靠,并鉴定出的49种化合物. |
| 关 键 词： | 干姜 挥发油 正交设计 |
| 收稿时间： | 2008-06-12 |
Studies on volatile oil extraction by orthogonal design and GC-MS analysis for Rhizoma Zingiberis |
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| LI Xiang,WU Hao,ZHU Dong-liang,CHAI Yi-feng and LOU Zi-yang. Studies on volatile oil extraction by orthogonal design and GC-MS analysis for Rhizoma Zingiberis[J]. The Journal of Pharmaceutical Practice, 2009, 27(1): 46-48,50 | |
| Authors: | LI Xiang WU Hao ZHU Dong-liang CHAI Yi-feng LOU Zi-yang |
| Affiliation: | Department of pharmaceutical analysis, School of pharmacy, Second military medical university, Shanghai 200433, China; Center of Disease prevention and Control, Beijing Military Region, Beijing 100042, China;Department of pharmaceutical analysis, School of pharmacy, Second military medical university, Shanghai 200433, China;Department of pharmaceutical analysis, School of pharmacy, Second military medical university, Shanghai 200433, China;Department of pharmaceutical analysis, School of pharmacy, Second military medical university, Shanghai 200433, China;Test centre, School of pharmacy, Second military medical university, Shanghai 200433, China |
| Abstract: | Objective: To optimize the extraction methods and GC-MS analysis of volatile oil in Rhizoma Zingiberis.Methods: The distilled water volume,ultrasonic time,soaking time and extraction time were optimized by orthogonal design and GC-MS chromatogram was obtained.Results:The yield of volatile oil was 1.89% by orthogonal design.Also,a stable,reliable chromatogram was obtained under optimized GC-MS conditions.Conclusion:The design can be applied for optimizing the extraction condition of volatile oil in Rhizoma Zingiberis and 49 compounds were identified by GC-MS analysis. |
| Keywords: | GC-MS |
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