Quantitative autoradiography of sodium-dependent [3H]D-aspartate binding sites in rat brain |
| |
| Authors: | B Parsons T C Rainbow |
| |
| Affiliation: | Department of Pharmacology, Medical school, University of Pennsylvania, Philadelphia, PA 19104 U.S.A. |
| |
| Abstract: | In vitro autoradiography was employed to localize and quantify Na-dependent [3H]d-aspartate binding sites in rat brain. LKB autoradiograms revealed a 15-fold variation in the concentration of [3H]d-aspartate binding sites among 40 brain regions. These results indicate that high-affinity uptakes sites for aspartic and/or glutamic acid are present ubiquitously, though not uniformlly, throughout the rat brain. |
| |
| Keywords: | autoradiography amino acids rat brain |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
