| 几种反义技术治疗胃癌的研究进展 |
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| 引用本文： | 饶建锋,罗忠金,张吉翔. 几种反义技术治疗胃癌的研究进展[J]. 国际消化病杂志, 2008, 28(5) |
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| 作者姓名： | 饶建锋 罗忠金 张吉翔 |
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| 作者单位： | 南昌大学第二附属医院消化内科,330006 |
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| 摘 要： | 研究表明,胃癌的形成与人端粒酶、热休克蛋白70(HSP70)、细胞周期素D1(cyclin D1)、bcl-2在胃癌细胞中的过表达密切相关。通过人端粒酶、HSP70、cyclin D1、bcl-2的反义基因可对其本身在胃癌细胞中的表达加以限制,从而达到治疗胃癌的目的。
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| 关 键 词： | 胃肿瘤 反义 基因疗法 |
Advances of several antisense methods for the treatment of stomach cancer |
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| RAO Jian-feng,LUO Zhong-jin,ZHANG Ji-xiang. Advances of several antisense methods for the treatment of stomach cancer[J]. International Journal of Digestive Disease, 2008, 28(5) |
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| Authors: | RAO Jian-feng LUO Zhong-jin ZHANG Ji-xiang |
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| Abstract: | Researches indicate that the stomach cancer formation has a close correlation with the high expression of the human telomerase, hot shock protein 70 (HSP70), cell cycle element D1(cyclin D1),bcl-2 in the stomach cancer cells. Using the human telomerase, HSP70, cyclin D1, bcl-2 antisense gene to limit themselves' expression in the stomach cancer cells and achieve the goal of stomach cancer therapy. |
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| Keywords: | Stomach neoplasm Antisense Gene therapy |
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