Evidence of Toscana virus circulation in Umbria: first report |
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Authors: | Francisci D Papili R Camanni G Morosi S Ferracchiato N Valente M Ciufolini M G Baldelli F |
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Affiliation: | (1) Clinica Malattie Infettive, Policlinico Monteluce, Dipartimento di Medicina Sperimentale e Scienze Biochimiche, Università degli Studi di Perugia, Perugia, Italy;(2) Arbovirus Unit, Laboratorio di Virologia, Istituto Superiore di Sanità, Roma |
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Abstract: | To evaluate, for the first time, circulation and clinical expression of Toscana virus (ToSv) in Umbria region we studied: (1) 93 cases of aseptic meningitis and meningoencephalitis admitted to our Department from 1989 to 2001 with negative results for common neurotropic virus; (2) 50 healthy subjects. Specific antibodies (IgM and IgG) anti-TOSv were found in 36.6% of aseptic meningitis, in 6.06% of meningoencephalitis and (IgG) in 16% of healthy subjects. |
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Keywords: | CNS diseases Toscana-virus circulation Umbria region |
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