中西医结合治疗高血压脑出血60例临床观察

目的观察中西医结合治疗高血压脑出血的临床疗效。方法将120例高血压脑出血患者随机分为2组,对照组60例应用西医常规治疗,治疗组60例在对照组治疗基础上应用通窍活血汤加味、补阳还五汤加减治疗。观察2组急性期再出血、死亡发生情况及2组治疗前后血肿吸收情况,比较2组治疗前后神经功能缺损评分(CNIS)变化及2组停药后90 d日常生活能力评分(ADL)变化。结果 2组急性期再出血率、死亡率比较差异无统计学意义(P0.05)。2组治疗结束后当日血肿吸收均优于本组治疗前(P0.05),且治疗组结束后当日血肿吸收优于对照组(P0.05)。2组治疗结束后当日、停药后90 d CNIS评分均较本组治疗前降低(P0.05),且治疗组降低更明显(P0.05)。治疗组停药后90 d ADL分级优于对照组(P0.05),治疗组日常生活能力优于对照组。结论中西医结合治疗高血压脑出血,可促进患者血肿吸收,且不增加急性期再出血风险及死亡率,更有利于患者预后。

Observation of combined therapy of traditional Chinese medicine and western medicine on hypertensive cere-bral hemorrhage

Objective To observe the clinical effect of combined therapy of traditional Chinese medicine and western medicine on hypertensive cerebral hemorrhage(HCH). Methods 120 HCH patients were randomly divid-ed into two groups. 60 patients in control group were treated by routine western medicine therapy. 60 patients in treat-ment group were treated by modified Tongqiao - huoxue decoction and Buyang - huanwu decoction on the basis of con-trol group treatment. The occurrences of acute rehemorrhage and death were observed in two groups,as well as the absorption of hematoma before and after treatment. The score of clinical neurological impairment scale CNIS before and after treatment was compared between two groups,as well as the changes of activities of daily living(ADL)90 d after drug withdrawal. Results There was no statistical significance between two groups on the acute rehemorrhage and death rate(P ﹥ 0. 05). The hematoma absorption after treatment that day was improved in two groups(P ﹤ 0. 05),and the improvement in treatment group was superior to that in control group(P ﹤ 0. 05). The score of CNIS the same day and 90 days after treatment was decreased in two groups(P ﹤ 0. 05),and the decrease in treatment group was more obvious(P ﹤ 0. 05). The degree of ADL 90 d after treatment in treatment group was superior to that in control group(P ﹤ 0. 05). Conclusion Combined therapy of traditional Chinese medicine and western medicine on the treatment of HCH,can promote the absorption of hematoma,without increase acute rehemorrhage and death rate,which is advantageous to the prognosis of patients.