Overgrowth and pruning of dendrites in adult rats recovering from neocortical damage. |
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Authors: | T A Jones T Schallert |
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Affiliation: | Department of Psychology, University of Texas, Austin 78712. |
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Abstract: | Unilateral lesions to the forelimb representation (FL) area of the rat sensorimotor cortex caused a time-dependent increase in the dendritic arborization of layer V pyramidal neurons in the contralateral homotopic cortex. The increase in arborization was maximum at 2-3 weeks after the lesion, following which there was a partial reduction in dendritic branching. These neural morphological changes may be related to post-lesion behavioral changes in the use of the forelimbs. |
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