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环孢素A联合沙利度胺治疗低危低增生性骨髓增生异常综合征疗效分析
引用本文:马清君,冷青,季征. 环孢素A联合沙利度胺治疗低危低增生性骨髓增生异常综合征疗效分析[J]. 中国医疗前沿, 2011, 0(2): 46+39-46,39
作者姓名:马清君  冷青  季征
作者单位:中国医科大学第六临床学院;辽宁省鞍山市中心医院血液科;
摘    要:目的分析环孢素A(CsA)联合沙利度胺治疗低危低增生性骨髓增生异常综合征(hypo-MDS)的临床疗效。方法应用CsA联合沙利度胺治疗21例低危hypo-MDS患者,随诊观察有效率及副作用发生情况。结果治疗后总有效率为76.2%(16/21),全部患者未发现严重毒副作用。结论 CsA联合沙利度胺治疗低危hypo-MDS患者安全、有效,但其长期疗效需进一步观察。

关 键 词:环孢素A  沙利度胺  骨髓增生异常综合征

Clinical Effect of Cyclosporin A Combined with Thalidomide on Low-risk Hypoplastic Myelodysplastic Syndrome
MA Qing-jun,LENG Qing,JI Zheng. Clinical Effect of Cyclosporin A Combined with Thalidomide on Low-risk Hypoplastic Myelodysplastic Syndrome[J]. China Healthcare Innovation, 2011, 0(2): 46+39-46,39
Authors:MA Qing-jun  LENG Qing  JI Zheng
Affiliation:MA Qing-jun,LENG Qing,JI Zheng.Department of Hematology,Six Hospital of Chinese Medical University,Anshan 114001,China
Abstract:Objective To observe the clinical effect of cyclosporin A(CsA) with thalidomide on low-risk hypoplastic myelodysplastic syndrome(hypo-MDS).Methods Twenty-one low-risk hypo-MDS patients receiving CsA with thalidomide treatment were followed up to observe the effectiveness and incidence of adverse reactions.Results The total effective rate of 21patients was 76.2%(16/21).No serious side effects were noted.Conclusion The combined CsA and thalidomide treatment is safe,effective in treatment of low-risk hypo-MDS,...
Keywords:Cyclosporin A  Thalidomide  Myelodysplastic syndrome  
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