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ATP Evokes Calcium Transients in Single Pulmonary Artery Endothelial Cell in
作者姓名:胡清华  王迪浔  张宇  陈荣三  王金唏
作者单位:HU Qing-hua,WANG Di-xun,ZHANG Yu,WANG Jin-xi,CHEN Rong-shan.(Department of Pathophysiology,Torgji Medical University Wuhan)(Department of Chemistry,Nanjin University.Nanjin)
摘    要:(胡清华)(王迪浔)(张宇)(陈荣三)(王金唏)ATPEvokesCalciumTransientsinSinglePulmonaryArteryEndothelialCellinPrimaryCultures¥HUQing-hua,WANGDi-...

收稿时间:26 May 1993

ATP evokes calcium transients in single pulmonary artery endothelial cell in primary cultures
Hu Qing-hua,Wang Di-xun,Zhang Yu,Wang Jin-xi,Chen Rong-shan.ATP Evokes Calcium Transients in Single Pulmonary Artery Endothelial Cell in[J].Journal of Zuazhong University of Science and Technology: Medical Edition,1994,14(1):42-44.
Authors:Hu Qing-hua  Wang Di-xun  Zhang Yu  Wang Jin-xi  Chen Rong-shan
Institution:(1) Department of Pathophysiology, Tongji Medical University, Wuhan;(2) Department of Chemistry, Nanjin University, Nanjin
Abstract:Effects of ATF on cytosclic free calcium (Ca2+]i) in single porcine pulmonary artery endothelia cell were studied.Using a dual-wavelength excitation on microflurometry.it was found that ATP evoked a rapid transient inCa2+]i which was then followed by a maintained elevation ofCa2+]i.The removal of extracellular Ca2+ abolished the maintained plateform, but exerted no obvious effect on the initial-transient.These results suggest that ATP stimulates both calcium release from intracellular calcium pool(s)and calcium influx across the Plasma membrane from extracellular space.
Keywords:cytosolic free calcium  endothelial cell  ATP
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