| 碱性磷酸酶在第三期牙本质形成过程中的分布及意义 |
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| 引用本文： | 文军,陆群,李齐宏. 碱性磷酸酶在第三期牙本质形成过程中的分布及意义[J]. 临床口腔医学杂志, 2009, 25(7): 398-401 |
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| 作者姓名： | 文军 陆群 李齐宏 |
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| 作者单位： | 广州军区广州总医院口腔科,广东,广州,510010;第四军医大学口腔医学院,陕西,西安,710032;解放军307医院,北京,100071 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 目的：观察碱性磷酸酶在第三期牙本质形成过程中的分布，探讨其在牙髓损伤修复过程中的作用及意义。方法：建立大鼠第三期牙本质形成动物模型，用免疫组织化学染色方法研究大鼠第三期牙本质形成过程中碱性磷酸酶的表达变化。结果：碱性磷酸酶于牙髓损伤早期阶段表达于穿髓点下方细胞群；随着修复性牙本质的形成其表达逐渐减弱直至消失。结论：碱性磷酸酶在牙髓损伤的早期阶段发挥着重要作用。
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| 关 键 词： | 碱性磷酸酶 牙髓炎 第三期牙本质 修复性牙本质 |
The immunolocalization and significance of alkaline phosphatase expression in tertiary dentinogenesis |
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| WEN Jun,LU Qun,Li Qi-hong. The immunolocalization and significance of alkaline phosphatase expression in tertiary dentinogenesis[J]. Journal of Clinical Stomatology, 2009, 25(7): 398-401 |
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| Authors: | WEN Jun LU Qun Li Qi-hong |
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| Affiliation: | WEN Jun,LU Qun,Li Qi-hong. Guangzhou General Hospital of Guangzhou Military Comm,,Guangdong Guangzhou 510010,China. |
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| Abstract: | Objective:Alkaline phosphatase(ALP)is present in matrix vesicles of mineralizing tissues and seems to be of significant importance in the initial formation of mineralized tissues. It is intimately involved in the development of calcified tooth tissue. Following a trauma,the dental pulp has an inherent capacity to produce tertiary dentin when the local environment is favorable to healing. The present study was to investigate the immunolocalization of ALP in the process of dental pulp injury and repair. Metho... |
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| Keywords: | alkaline phosphatase pulpitis tertiary dentin reparative dentin |
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