羊膜移植治疗眼表烧伤的临床应用分析

目的:评价羊膜移植治疗眼表化学烧伤及热烧伤的临床疗效。方法:收集我院眼部化学及热烧伤24例28眼,行新鲜羊膜移植术治疗,随访6～24mo。术后观察视力,羊膜移植片情况,角膜恢复情况及角膜上皮修复时间,并发症。结果:术后视力提高者22眼(79%),不变者6眼(21%),无视力下降者,术前术后视力差别无统计学意义。羊膜移植片情况:28眼中羊膜覆盖成活24眼,成活率达86%。角膜恢复情况:28眼中角膜最终恢复透明8眼,角膜云翳12眼,角膜斑翳5眼,角膜白斑3眼。角膜上皮愈合时间:22眼角膜上皮1～3wk全部愈合。术前4眼睑球粘连患者,睑球粘连情况均得到改善,3眼完全分离。结论:新鲜羊膜移植术是治疗眼表化学及热烧伤的有效方法。

Clinical application effect analysis of amniotic membrane grafting for ocular surface burn

AIM:To evaluate the clinical curative effect of amniotic membrane grafting for ocular chemical burn and thermal burn. ·MEHTODS:We collected 24 patients 28 eyes with ocular chemical and thermal burn,which had been treated with amniotic membrane grafting in our hospital. The follow-up time ranged from 6-24 months. The posto-perative visual acuity,the condition of amniotic mem-brane transplant,renovation of cornea,healing time of corneal epithelium and complication were observed. ·RESULTS:Postoperative corrected visual acuity:visual acuity was improved in 22 eyes(79%)and was not changed in 6 eyes(21%)after amniotic membrane grafting,no visual acuity appearances declined,and there was no statistical significance between preoperative visual acuity and postoperative visual acuity. Status of amniotic membrane implant:amniotic membrane survived in 24 eyes and the survival rate was up to 86%.Conditions of cornea:8 eyes recovered to transparent; nebula emerged in 12 eyes eventually,corneal macula emerged in 5 eyes and 3 eye ended up with leukoma. Time of corneal epi-thelium healing:corneal epithelium of 28 eyes recovered entirely,22 eyes of which recovered within 3 weeks. Symblepharon condition improved in all 4 patients who suffered from preoperative atretoblepharia,including three cases completely separate. ·CONCLUTION:Amniotic membrane grafting is an effective method to deal with ocular surface burn.