| 大鼠急性脊髓损伤后GFAP和VEGF表达及相关性 |
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| 引用本文： | 祝恺,李锋,解思信. 大鼠急性脊髓损伤后GFAP和VEGF表达及相关性[J]. 齐鲁医学杂志, 2011, 26(1): 49-50 |
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| 作者姓名： | 祝恺 李锋 解思信 |
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| 作者单位： | 1. 青岛市第九人民医院骨科,山东,青岛,266002
2. 华中科技大学同济医学院附属同济医院骨科 |
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| 摘 要： | 目的 观察大鼠急性脊髓损伤后胶质纤维酸性蛋白(GFAP)和血管内皮生长因子(VEGF)的表达变化,并分析其相关性.方法 SD大鼠36只,随机分为损伤后6 h、12 h、1 d、3 d、7 d组及假手术组共 6 组,每组6只,其中假手术组只做椎板切除.采用免疫组化SABC法检测GFAP和VEGF的动态表达情况,并进行相关...
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| 关 键 词： | 脊髓损伤 神经胶质原纤维酸性蛋白质 血管内皮生长因子A 大鼠 |
THE EXPRESSIONS OF GFAP AND VEGF AFTER ACUTE SPINAL CORD INJURY AND THEIR CORRELATION IN RATS |
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| ZHU KAI,LI FENG,XIE SI-XIN. THE EXPRESSIONS OF GFAP AND VEGF AFTER ACUTE SPINAL CORD INJURY AND THEIR CORRELATION IN RATS[J]. Medical Journal of Qilu, 2011, 26(1): 49-50 |
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| Authors: | ZHU KAI LI FENG XIE SI-XIN |
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| Affiliation: | ZHU KAI,LI FENG,XIE SI-XIN(Department of Orthopedics,No.9 People's Hospital of Qingdao,Qingdao 266002,China) |
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| Abstract: | Objective To observe the expressions of glial fibrillary acidic protein(GFAP) and vascular endothelial growth factor(VEGF) after acute spinal cord injury(ASCI) in rats,and analyze their correlation. Methods Thirty-six SD rats were evenly divided into six groups,e.i.,groups of 6 h,12 h,1 d,3 d,7 d after spinal cord injury and sham operation group.The rats in sham-operation group underwent vertebral plate removal only.SABC immunohistochemical technique was used to detect the expressions of GFAP and VEGF,their... |
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| Keywords: | spinal cord injury glial fibrillary acidic protein vascular endothelial growth factor A rats |
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