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Bayesian transformation cure frailty models with multivariate failure time data
Authors:Yin Guosheng
Institution:Department of Biostatistics, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. gsyin@mdanderson.org
Abstract:We propose a class of transformation cure frailty models to accommodate a survival fraction in multivariate failure time data. Established through a general power transformation, this family of cure frailty models includes the proportional hazards and the proportional odds modeling structures as two special cases. Within the Bayesian paradigm, we obtain the joint posterior distribution and the corresponding full conditional distributions of the model parameters for the implementation of Gibbs sampling. Model selection is based on the conditional predictive ordinate statistic and deviance information criterion. As an illustration, we apply the proposed method to a real data set from dentistry.
Keywords:Bayesian inference  Box–Cox transformation  correlated survival data  cure rate model  model selection
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