颈动脉狭窄和缺血性脑血管病关系的研究

目的　探讨动脉粥样硬化所致的颈动脉颅外段狭窄与缺血性脑血管疾病的关系。方法　对214例脑梗死(CI)患者、26例短暂性脑缺血发作(TIA)患者、58例单纯高血压病(HBP)患者及43例正常健康人群,通过颈动脉彩色多普勒超声检测颈动脉颅外段的狭窄程度,并结合其病史进行对照研究。结果　CI、TIA患者的颈动脉颅外段狭窄率(分别为78.98%、57.69%)较HBP组(46.30%)和正常对照组(30.95%)明显升高(P <0.01,P <0.05),狭窄程度在1%~50%;CI各年龄组间狭窄程度无明显差异(P >0.05),但50岁以上的老年患者颈动脉狭窄率明显高于50 岁以下的患者(P <0.01);TIA与CI患者颈动脉狭窄度有症状侧重于无症状侧。结论　缺血性脑血管病与颈动脉狭窄程度有明显相关性。

Study of the Correlation Between Carotid Artery Stenosis and Ischemic Cerebrovascular Disease

Objective To explore the correlation between ischemic stroke and extracranial carotid artery stenosis caused by arteriosclerosis. Methods 214 patients with CI and 26 patients with TIA were brought into the trial, and 58 patients with hypertension (HBP) and 43 healthy people were selected as the control groups. The extracranial carotid artery was detected by color doppler sonographer. And all cases were evaluated combining with case history. Results The incidence of carotid artery stenosis in CI, TIA cases, HBP and healthy control groups were 78.98%, 57.69%, 46.30%, 30.95% respectively. The carotid artery stenosis in CI and TIA patients was more serious than the other two groups (P<0.01 and P<0.05). The degree of stenosis was from 1% to 50%. The degree of stenosis in the several age groups of CI was not significantly different (P>0.05), but the incidence of carotid artery stenosis in patients more than fifty years old was significantly higher than it in the other patients (P<0.01). In CI and TIA cases, the degree of carotid artery stenosis in side of symptom was more serious than the other side. Conclusions The study demonstrated there was significant correlation between ischemic stroke and carotid artery stenosis caused by arteriosclerosis.