药物流产后加服米索前列醇对流产结局影响的临床分析

目的观察常规药物流产后加服米索前列醇对流产结局的影响。方法将300例早孕妇女分为观察组（150例）和对照组（150例）。常规药物流产用药后，口服米索前列醇600μg。观察组于口服米索前列醇6小时后加服米索前列醇600μg，对照组不再加服。结果完全流产率观察组为97．33％，对照组为88．67％，两组间有显著性差异（P〈0．05），平均阴道出血时间，观察组（8．8±4．1）d，对照组（15．8±5．2）d，两组间有显著差异（P〈0．05），阴道出血量两组间有显著差异（P〈0．05），不良反应两组无显著差异（P〉0．05）。结论加服米索前列醇可提高完全流产率，缩短药物流产后阴道出血时间和减少出血量，加药后不增加不良反应，是值得推广的药物流产方法。

Clinical analysis of the effect on abortion outcomes about adding Misoprostol after routine medical abortion

Objective To study the effect on the abortion outcomes about adding misoprostol after routine medical abortion. Methods 300 early pregnant women were divided into study group and control group. 150 patients were treated with Misoprostol 600 μg after 6 hours of routine medical abortion with Misoprostol in the study group while other 150 patients were given no other medicine. Results There was significant difference between two groups（P 〈0.05） on the complete abortion rate that it was 97. 33% in study group and 88.67% in control group. The mean durations of vaginal bleeding was （ 8.8 ± 4. 1 ） - day in study group and （ 15. 8 ±5.2） - day in control group. There was significant difference between two groups（ P 〈 0. 05）. There was no difference on the adverse reactions between two groups （ P 〈 0. 05）. Conclusion The complete abortion rate was increased and the mean duration of vaginal bleeding was shortened by adding Misoprostol after medical abortion and meanwhile the adverse reaction was unchanged. It was worth generalizing of medical abortion.