糖尿病高危人群风险因素对照研究

目的 分析糖尿病有关危险因素间的差异显著性。方法 2003名无症状,但有明确糖尿病危险因素,包括家族糖尿病史、肥胖、高血压、高血脂、女性巨大胎儿史为筛检对象。来自相同社区无糖尿病危险因素的5362人作为对照。结果 接受筛检的2003人中,131人被诊断有糖尿病,占6.54％。在上述人群中,有1种糖尿病危险因素的为1547人,占77.23％;有2种危险因素的为387人,占19.27％;有3种以上危险因素的70人,占3.49％。对照组5362人中,96人被诊断有糖尿病,占1.79％。和对照组相比,有明显危险因素的2003人在年龄标化后患糖尿病的OR值(95％CI)为2.68(2.20～3.25)。有1种危险因素的人患糖尿病的OR值为2.89,而有3种以上危险因素的OR值则增加到4.68。结论 高危人群罹患糖尿病的风险和具备危险因素量呈正相关,有必要在这些高危人群中开展早期、规则的糖尿病筛检。

The control study on risk factors of high-risk population in diabetes

Objective To examine the significance of individual risk on diabetes to subjects who underwent diabetes screening. Methods 2003 asymptomatic diabetes subjects with high-risk factors of diabetes as family history, obesity, hypertension, and/or dysipidemia, fetal giant history were screened. 5362 subjects having no risk factors but from the same community were allocated as controls. Results There were 131(6.54%) diabetes identified in the screening group and 1547(77.23%) subjects having 1 risk factor,387(19.27%) having 2 risk factors, 70 (3.49%) having 3 or more risk factors. There were 96 (1.79%) diabetes identified in the control group. Compared with control group, the OR (95% CI) value was 2. 68(2. 20-3.25)after adjusted on age among the high risk group. The OR value of those having 1 risk factor was 2. 89, but these having 3 or more risk factors increased to 4. 68. Conclusion The relation betwee the risk of high-risk group with diabetes and the number of risk factors of diabetes presented positive correlation. Early and regular screening for diabetes was essential in these individuals with high-risk factors.