| 女性外阴尖锐湿疣及湿疣样病变组织中人类乳头瘤病毒 DNA 的检测 |
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| 引用本文： | 单爱琳,余秀梅.女性外阴尖锐湿疣及湿疣样病变组织中人类乳头瘤病毒 DNA 的检测[J].首都医学院学报,1993,14(3):171-174. |
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| 作者姓名： | 单爱琳 余秀梅 |
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| 作者单位： | 首都医学院电镜室，首都医学院电镜室，首都医学院电镜室，首都医学院附属北京红十字朝阳医院，首都医学院附属北京红十字朝阳医院，首都医学院附属北京红十字朝阳医院 |
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| 摘 要： | 用生物素和~(32)P-人类乳头瘤病毒 HPV11、HPV16和 HPV18型 DNA 探针,以斑点和 SouthernBlot 杂交方法检测了49例北京地区女性外阴尖锐湿疣和湿疣样病变组织中 HPV DNA。在24例尖锐湿疣组织中,HPV DNA 阳性者为18例(75%);其中 HPV11 DNA 阳性者16例,占阳性例数的88.9%;HPV16 DNA 阳性者2例,占阳性例数的11.1%;没有发现 HPV18 DNA 阳性者.25例湿疣样病变组织中,8例含有 HPV DNA(32%),全为 HPV11型。本文对湿疣样病变与 HPV 感染的关系,外阴部尖锐湿疣的分型及诊断标准进行了初步探讨。
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| 关 键 词： | 尖锐湿疣 人类乳头瘤病毒 核酸杂交 湿疣样病变 |
| 收稿时间： | 1992-03-19 |
The Detection of DNA Type of Human Papilloma Virus in Condylomata Acuminata and Condylomalike Vulvar Lesions |
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| Shan Ailin Gao Jianping Gao Tianxing.The Detection of DNA Type of Human Papilloma Virus in Condylomata Acuminata and Condylomalike Vulvar Lesions[J].Journal of Capital University of Medical Sciences,1993,14(3):171-174. |
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| Authors: | Shan Ailin Gao Jianping Gao Tianxing |
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| Institution: | Shan Ailin Gao Jianping Gao Tianxing Department of Electron Microscope,Capital Institute of Medicine
Yu Xiumei Song Xuehong Tang Xiaonai Beijing Red Cross Chaoyang Hospital,Capital Institute of Medicine |
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| Abstract: | 40 cases(24 condylomata acuminata,25 condylomalike vulvar lesions)are examined for HPV DNA type by Dot and Southern Blot hybridization.75% of condylomata acuminata is positive,and 88.9% of positive cases is HPV11 type while 11.1% is of HPV 16 type.Com- paring with condylomata acuminata,only 32% of 25 condylomalike vulvar lesions contains HPV type 11 DNA.The classification,diagnostic criteria of condylomata acuminata as well as eitiology of condylomalike vulvar lesions are discussed. |
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| Keywords: | condylomata acuminata human papilloma virus hybridization of nucleic acid condylomalike vulvar lesion |
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