经肺温度稀释法在肝及其与肾、胰、十二指肠联合移植围术期的应用研究

目的:观察经肺温度稀释法(PiCCO技术)在肝及其与肾、胰、十二指肠联合移植手术围术期的应用情况,并与改良式肺动脉漂浮导管(CCO导管)比较反映心脏前负荷参数的有效性。方法:对2例实施肝移植,1例实施肝脏、胰腺、十二指肠移植术,1例实施肝肾联合移植术的患者进行研究,4例患者均为男性,年龄42～48岁,ASAⅢ～Ⅳ级。无PiCCO及CCO导管置入禁忌证。静脉注射咪唑安定、异丙酚、芬太尼、维库溴胺后经鼻气管插管。于麻醉诱导前、气管插管后、切皮、无肝前期、无肝期、新肝前期、新肝期、术毕及术后血流动力学发生变化时,通过温度稀释法同时测定PiCCO与CCO系列参数。结果:共测得数据135组,其中全心舒张末期容积指数(GEDI)与每搏量指数正相关(r=0.77,P<0.001),肺动脉阻塞压与GEDI相关(r=0.44,P<0.05),中心静脉压与GEDI不相关(r=0.24,P>0.05);两种方法心输出量指数结果对比差异无统计学意义(P>0.05)。SVI与GEDI之间Pearson相关系数为r=0.77(P<0.001)。结论:在上腹部单或多器官移植围术期应用PiCCO技术可准确测量心输出量,其所测量的全心舒张末期...

Application of transpulmonary thermodilution method in patients undergoing liver or liver plus other organs transplantation

Objective To investigate the application of transpulmonary thermodilution method during the peri- operation of simultaneous orthotopic liver and heterotopic pancreas- duodenum transplantations, and compare the efficiency in monitoring the preload of heart with improved Swan- Ganz CCO- SvO2 method. Methods Four male patients (age: 42～ 48, ASA Ⅲ ～ Ⅳ ) were involved in the study: 2 had liver transplantation, 1 had liver and pancreas- duodenum transplantations and 1 had simultaneous liver and kidney transplanta...