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颅脑损伤后早期高氧液治疗的疗效评价及其作用机制探讨
引用本文:周德祥,郑丰任,杨应明,袁军,赖润龙,许锦成.颅脑损伤后早期高氧液治疗的疗效评价及其作用机制探讨[J].昆明医学院学报,2004,25(3):50-52.
作者姓名:周德祥  郑丰任  杨应明  袁军  赖润龙  许锦成
作者单位:广东省汕头市汕大医学院第一附属医院神经外科,汕头,515041
摘    要:目的 :评价颅脑损伤后早期高氧液治疗的临床疗效 ,并对其作用机制加以探讨 .方法 :136例颅脑损伤随机分为高氧液组和常规治疗组 ,比较两组的临床疗效及意识恢复情况 .结果 :高氧液组的临床疗效及意识恢复明显优于常规治疗组 ,分别为P >0 0 5和P >0 0 1.结论 :高氧液能改善脑缺血缺氧状态 ,减轻颅脑损伤后的继发性脑损伤 ,加速神经功能的恢复 ,促进觉醒 ,提高疗效 ,改善预后 ,值得推广

关 键 词:高氧液  常规治疗  颅脑损伤  早期  作用机制  疗效评价  临床疗效  推广  改善  恢复
文章编号:1003-4706(2004)03-0050-03
修稿时间:2004年6月6日

Evaluation of the Clinical Curative Effect of Early High-oxygen Liquid Therapy on Cerebral Injury and Discussion of Its Active Mechanisms
ZHOU De-xiang,ZHENG Feng-ren,YANG Ying-ming,YUAN Jun,LAI Run-long,XU Jing-cheng.Evaluation of the Clinical Curative Effect of Early High-oxygen Liquid Therapy on Cerebral Injury and Discussion of Its Active Mechanisms[J].Journal of Kunming Medical College,2004,25(3):50-52.
Authors:ZHOU De-xiang  ZHENG Feng-ren  YANG Ying-ming  YUAN Jun  LAI Run-long  XU Jing-cheng
Abstract:Objective: The purpose of this article is to evaluate the clinical curative effect of early high-oxygen liquid therapy on cerebral injury and discuss its active mechanisms. Methods: 136 cases of cerebral injury were divided randomly into two groups, high-oxygen liquid therapy group and comparison one. Then, the clinical curative effect and recovery consciousness were compared. Results: The clinical curative effect and recovery consciousness in high-oxygen liquid therapy group were better than those in comparison one P>0.05 and P>0.01. Conclusion: High-oxygen liquid therapy can remedy ischemia and anoxia. Further, lessen cerebral secondary injury. It is benefit for recovery of nerve function and consciousness as well as ameliorating the clinical outcome following cerebral injury.
Keywords:High-oxygen liquid  Cerebral injury  Clinical curative effect
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