Acute Liver Failure due to Non-Hodgkin's Lymphoma |
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| Authors: | J. Saló ,M.D.,,B. Nomdedeu,M.D.,,M. Bruguera,M.D.,,J. Ordi,M.D.,,P. Ginè s,M.D.,,A. Castells,M.D.,,A. Vilella,M.D., J. Rodé s,M.D. |
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| Affiliation: | Liver Unit. Hematology Department, and Pathology Department, Hospital Clinic i Provincial, Universitat de Barcelona, Catalunya, Spain |
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| Abstract: | Acute hepatic failure secondary to involvement of the liver by hematologic malignancies is a very uncommon condition, and usually has a fatal prognosis. We describe the case of a woman who developed acute hepatic failure due to infiltration by a non-Hodgkin's lymphoma 18 yr after the initial diagnosis of a nodular-type lymphocytic lymphoma, while she was apparently in remission. Early diagnosis was achieved through liver biopsy; therefore, rapid administration of chemotherapy allowed her complete recovery. Hepatic biopsy may provide a diagnosis in patients in whom the etiology of liver failure is unknown, thus establishing the possible need for specific treatment. |
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