Localization of common (cross-reacting) antigens with Neisseria perflava and Klebsiella pneumoniae in tissues of the human bronchopulmonary apparatus

Antigenic similarity was studied between the microsomal fraction of tissues of the human bronchopulmonary apparatus and bacterial cells living in the respiratory tract:Neisseria perflava andKlebsiella pneumoniae. Cross reactions were studied with antimicrosomal sera in the complement fixation test withN. perflava andK. pneumoniae. Fixation of antibacterial antibodies and antibodies against microsomal fractions of the lung tissues was investigated in tissue sections of the human lungs and bronchi. The presence of antigens cross reacting with the antimicrobial sera was demonstrated in the microsomal fraction of tissues of the human bronchopulmonary apparatus.Allergologic Research Laboratory, Academy of Medical Sciences of the USSR, Moscow. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 2, pp. 210–212, February, 1976.