曼月乐治疗子宫腺肌病98例疗效分析

目的 探讨曼月乐治疗子宫腺肌病临床效果.方法 98例子宫腺肌病患者应用曼月乐治疗,随访观察并比较患者放置前及放置后1、3、6、9个月后痛经程度、月经量及经期变化.结果 98例患者放置曼月乐1、3个月后痛经评分分别为(1.20±0.15)、(0.10±0.02)分,比放置前(2.20±0.35)分明显降低,差异有统有统计学意义(P<0.05),6个月后痛经消失.放置曼月乐1个月后月经量(78±30)mL]较放置前(112±52)mL]明显减少,差异有统计学意义(P<0.05),3、6、9个月后月经量持续下降,其中16例9个月后闭经.放置曼月乐后1个月平均经期(11.5±3.1)d]较放置前(6.1±2.8)d]明显延长,差异有统计学意义(P<0.05),3个月后(6.9±2.0)d]恢复到放置前水平,差异无统计学意义(P＞0.05),6个月后(3.9±1.1)d]明显短于放置前(P<0.05).结论 宫内放置曼月乐能有效缓解子宫腺肌病患者的痛经症状、保留子宫.是治疗子宫腺肌病一种安全、有效的微创方法.

The Analysis of LNG-IUS in the Treatment of 98 Adenomyosis

Objective To investigate the clinical efficacy of levonorgestrel-releasing intrauterine system（LNG-IUS）in treating adenomyosis.Methods Ninty-eight patients with adenomysois were followed up in 1,3,6,9 months after placing LNG-IUS dysmenorrhea,menstrual blood volume and menstrual period were compared.Results Ninty-eight patients had alleviated dysmenorrhea obviously after placing LNG-IUS in one month and three months with significantly less scores （1.20±0.15）、（0.10±0.02）scores] by dysmenorrhea grading than before（2.20±0.35） scores]（P0.05）,after six months,dysmenorrhea disappeared.Andmenstrual blood volume of the patients after placing LNG-IUS in one month decreased remarkably（P0.05）,which reduced from （112±52）mL]to （78±30）mL],and went on declined after 3、6、9 months,16 menostasis after 9 months.The patients menstrual period were evidently longer after LNG-IUS placed for one month （11.5±3.1）d] than before（6.1±2.8）d]（P0.05）,but fell back to primary state after three months（16.9±2.0）d,P0.05],and were shorter significantly than before after six months（3.9±1.1）d]（P0.05）.Conclusions LIG-IUS placed in uterus is an safe,effective and micro-invasive therapy for adenomyosis,which can effectively relieve dysmenorrhea as well as uterine preservation,cut down menstrual blood volume and shorten menstrual period.